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Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming
Munc18-1 and soluble NSF attachment protein receptors (SNAREs) are critical for synaptic vesicle fusion. Munc18-1 binds to the SNARE syntaxin-1 folded into a closed conformation and to SNARE complexes containing open syntaxin-1. Understanding which steps in fusion depend on the latter interaction an...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Rockefeller University Press
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2686405/ https://ncbi.nlm.nih.gov/pubmed/19255244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200812026 |
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