Association of hepcidin promoter c.-582 A>G variant and iron overload in thalassemia major

Hepcidin is a 25-amino acid peptide, derived from cleavage of an 84 amino acid pro-peptide produced predominantly by hepatocytes. This molecule, encoded by the hepcidin antimicrobial peptide (HAMP) gene shows structural and functional properties consistent with a role in innate immunity. Moreover, a...

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Bibliografiske detaljer
Main Authors: Andreani, Marco, Radio, Francesca Clementina, Testi, Manuela, De Bernardo, Carmelilia, Troiano, Maria, Majore, Silvia, Bertucci, Pierfrancesco, Polchi, Paola, Rosati, Renata, Grammatico, Paola
Format: Artigo
Sprog:Inglês
Udgivet: Ferrata Storti Foundation 2009
Fag:
Brief Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738723/
https://ncbi.nlm.nih.gov/pubmed/19734422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.006270
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