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Hepcidin gene polymorphisms and iron overload in β-thalassemia major patients refractory to iron chelating therapy

BACKGROUND: β Thalassemia is one of the most common groups of hereditary haemoglobinopathies. Affected people with thalassemia major are dependent on regular blood transfusion which on the long term leads to iron overload. Hepcidin is a peptide hormone and an important regulator of iron homeostasis,...

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Bibliografiske detaljer
Udgivet i:BMC Med Genet
Main Authors: Zarghamian, Parinaz, Azarkeivan, Azita, Arabkhazaeli, Ali, Mardani, Ahmad, Shahabi, Majid
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140315/
https://ncbi.nlm.nih.gov/pubmed/32268883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-020-01011-3
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