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Hepcidin gene polymorphisms and iron overload in β-thalassemia major patients refractory to iron chelating therapy

BACKGROUND: β Thalassemia is one of the most common groups of hereditary haemoglobinopathies. Affected people with thalassemia major are dependent on regular blood transfusion which on the long term leads to iron overload. Hepcidin is a peptide hormone and an important regulator of iron homeostasis,...

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Dades bibliogràfiques
Publicat a:BMC Med Genet
Autors principals: Zarghamian, Parinaz, Azarkeivan, Azita, Arabkhazaeli, Ali, Mardani, Ahmad, Shahabi, Majid
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140315/
https://ncbi.nlm.nih.gov/pubmed/32268883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-020-01011-3
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