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Molecular Characterization of Clinical Isolates of Human Immunodeficiency Virus Resistant to the Protease Inhibitor Darunavir

Darunavir is the most recently approved human immunodeficiency virus (HIV) protease (PR) inhibitor (PI) and is active against many HIV type 1 PR variants resistant to earlier-generation PIs. Darunavir shows a high genetic barrier to resistance development, and virus strains with lower sensitivity to...

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Bibliografische gegevens
Hoofdauteurs: Šašková, Klára Grantz, Kožíšek, Milan, Řezáčová, Pavlína, Brynda, Jiří, Yashina, Tatyana, Kagan, Ron M., Konvalinka, Jan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738195/
https://ncbi.nlm.nih.gov/pubmed/19535439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00451-09
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