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Molecular Characterization of Clinical Isolates of Human Immunodeficiency Virus Resistant to the Protease Inhibitor Darunavir

Darunavir is the most recently approved human immunodeficiency virus (HIV) protease (PR) inhibitor (PI) and is active against many HIV type 1 PR variants resistant to earlier-generation PIs. Darunavir shows a high genetic barrier to resistance development, and virus strains with lower sensitivity to...

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Bibliografiska uppgifter
Huvudupphovsmän: Šašková, Klára Grantz, Kožíšek, Milan, Řezáčová, Pavlína, Brynda, Jiří, Yashina, Tatyana, Kagan, Ron M., Konvalinka, Jan
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738195/
https://ncbi.nlm.nih.gov/pubmed/19535439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00451-09
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