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Molecular Characterization of Clinical Isolates of Human Immunodeficiency Virus Resistant to the Protease Inhibitor Darunavir

Darunavir is the most recently approved human immunodeficiency virus (HIV) protease (PR) inhibitor (PI) and is active against many HIV type 1 PR variants resistant to earlier-generation PIs. Darunavir shows a high genetic barrier to resistance development, and virus strains with lower sensitivity to...

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主要な著者: Šašková, Klára Grantz, Kožíšek, Milan, Řezáčová, Pavlína, Brynda, Jiří, Yashina, Tatyana, Kagan, Ron M., Konvalinka, Jan
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738195/
https://ncbi.nlm.nih.gov/pubmed/19535439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00451-09
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