Molecular Characterization of Clinical Isolates of Human Immunodeficiency Virus Resistant to the Protease Inhibitor Darunavir

Darunavir is the most recently approved human immunodeficiency virus (HIV) protease (PR) inhibitor (PI) and is active against many HIV type 1 PR variants resistant to earlier-generation PIs. Darunavir shows a high genetic barrier to resistance development, and virus strains with lower sensitivity to...

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Detalhes bibliográficos
Main Authors: Šašková, Klára Grantz, Kožíšek, Milan, Řezáčová, Pavlína, Brynda, Jiří, Yashina, Tatyana, Kagan, Ron M., Konvalinka, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738195/
https://ncbi.nlm.nih.gov/pubmed/19535439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00451-09
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