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Ninety-Nine Is Not Enough: Molecular Characterization of Inhibitor-Resistant Human Immunodeficiency Virus Type 1 Protease Mutants with Insertions in the Flap Region

While the selection of amino acid insertions in human immunodeficiency virus (HIV) reverse transcriptase (RT) is a known mechanism of resistance against RT inhibitors, very few reports on the selection of insertions in the protease (PR) coding region have been published. It is still unclear whether...

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Detalhes bibliográficos
Main Authors: Kožíšek, Milan, Šašková, Klára Grantz, Řezáčová, Pavlína, Brynda, Jiří, van Maarseveen, Noortje M., De Jong, Dorien, Boucher, Charles A., Kagan, Ron M., Nijhuis, Monique, Konvalinka, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2395164/
https://ncbi.nlm.nih.gov/pubmed/18400858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02325-07
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