Mutations in HIV-1 gag and pol Compensate for the Loss of Viral Fitness Caused by a Highly Mutated Protease

During the last few decades, the treatment of HIV-infected patients by highly active antiretroviral therapy, including protease inhibitors (PIs), has become standard. Here, we present results of analysis of a patient-derived, multiresistant HIV-1 CRF02_AG recombinant strain with a highly mutated pro...

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Detalhes bibliográficos
Main Authors: Kožíšek, Milan, Henke, Sandra, Šašková, Klára Grantz, Jacobs, Graeme Brendon, Schuch, Anita, Buchholz, Bernd, Müller, Viktor, Kräusslich, Hans-Georg, Řezáčová, Pavlína, Konvalinka, Jan, Bodem, Jochen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421615/
https://ncbi.nlm.nih.gov/pubmed/22644035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00465-12
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