Formation of a Quaternary Complex of HIV-1 Reverse Transcriptase with a Nucleotide-competing Inhibitor and Its ATP Enhancer

Por Ehteshami, Maryam, Nijhuis, Monique, Bernatchez, Jean A., Ablenas, Christopher J., McCormick, Suzanne, de Jong, Dorien, Jochmans, Dirk, Götte, Matthias
Publicado em 2013

Modulation of HIV-1 Gag NC/p1 cleavage efficiency affects protease inhibitor resistance and viral replicative capacity

Por van Maarseveen, Noortje M, Andersson, Dan, Lepšík, Martin, Fun, Axel, Schipper, Pauline J, de Jong, Dorien, Boucher, Charles AB, Nijhuis, Monique
Publicado em 2012

GS-8374, a Prototype Phosphonate-Containing Inhibitor of HIV-1 Protease, Effectively Inhibits Protease Mutants with Amino Acid Insertions

Por Grantz Šašková, Klára, Kožíšek, Milan, Stray, Kirsten, de Jong, Dorien, Řezáčová, Pavlína, Brynda, Jiří, van Maarseveen, Noortje M., Nijhuis, Monique, Cihlář, Tomáš, Konvalinka, Jan
Publicado em 2014

A combinational CRISPR/Cas9 gene-editing approach can halt HIV replication and prevent viral escape

Por Lebbink, Robert Jan, de Jong, Dorien C. M., Wolters, Femke, Kruse, Elisabeth M., van Ham, Petra M., Wiertz, Emmanuel J. H. J., Nijhuis, Monique
Publicado no Sci Rep (2017)

Differential In Vitro Kinetics of Drug Resistance Mutation Acquisition in HIV-1 RT of Subtypes B and C

Por Cunha, Rodrigo D., Abreu, Celina M., Gonzalez, Luis M. F., Nijhuis, Monique, de Jong, Dorien, Aguiar, Renato S., Afonso, Adriana O., Brindeiro, Rodrigo M., Tanuri, Amilcar
Publicado em 2012

Ninety-Nine Is Not Enough: Molecular Characterization of Inhibitor-Resistant Human Immunodeficiency Virus Type 1 Protease Mutants with Insertions in the Flap Region

Por Kožíšek, Milan, Šašková, Klára Grantz, Řezáčová, Pavlína, Brynda, Jiří, van Maarseveen, Noortje M., De Jong, Dorien, Boucher, Charles A., Kagan, Ron M., Nijhuis, Monique, Konvalinka, Jan
Publicado em 2008

Persistence of frequently transmitted drug-resistant HIV-1 variants can be explained by high viral replication capacity

Por Pingen, Marieke, Wensing, Annemarie MJ, Fransen, Katrien, De Bel, Annelies, de Jong, Dorien, Hoepelman, Andy IM, Magiorkinis, Emmanouil, Paraskevis, Dimitrios, Lunar, Maja M, Poljak, Mario, Nijhuis, Monique, Boucher, Charles AB
Publicado no Retrovirology (2014)

A Novel Substrate-Based HIV-1 Protease Inhibitor Drug Resistance Mechanism

Por Nijhuis, Monique, van Maarseveen, Noortje M, Lastere, Stephane, Schipper, Pauline, Coakley, Eoin, Glass, Bärbel, Rovenska, Mirka, de Jong, Dorien, Chappey, Colombe, Goedegebuure, Irma W, Heilek-Snyder, Gabrielle, Dulude, Dominic, Cammack, Nick, Brakier-Gingras, Lea, Konvalinka, Jan, Parkin, Neil, Kräusslich, Hans-Georg, Brun-Vezinet, Francoise, Boucher, Charles A. B
Publicado em 2007