Persistence of frequently transmitted drug-resistant HIV-1 variants can be explained by high viral replication capacity

BACKGROUND: In approximately 10% of newly diagnosed individuals in Europe, HIV-1 variants harboring transmitted drug resistance mutations (TDRM) are detected. For some TDRM it has been shown that they revert to wild type while other mutations persist in the absence of therapy. To understand the mech...

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Vydáno v:Retrovirology
Hlavní autoři: Pingen, Marieke, Wensing, Annemarie MJ, Fransen, Katrien, De Bel, Annelies, de Jong, Dorien, Hoepelman, Andy IM, Magiorkinis, Emmanouil, Paraskevis, Dimitrios, Lunar, Maja M, Poljak, Mario, Nijhuis, Monique, Boucher, Charles AB
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263067/
https://ncbi.nlm.nih.gov/pubmed/25575025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-014-0105-9
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