Formation of a Quaternary Complex of HIV-1 Reverse Transcriptase with a Nucleotide-competing Inhibitor and Its ATP Enhancer

Nucleotide-competing reverse transcriptase inhibitors were shown to bind reversibly to the nucleotide-binding site of the reverse transcriptase (RT) enzyme of human immunodeficiency virus type 1 (HIV-1). Here, we show that the presence of ATP can enhance the inhibitory effects of the prototype compo...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ehteshami, Maryam, Nijhuis, Monique, Bernatchez, Jean A., Ablenas, Christopher J., McCormick, Suzanne, de Jong, Dorien, Jochmans, Dirk, Götte, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682535/
https://ncbi.nlm.nih.gov/pubmed/23598281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.433441
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados