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Allosteric Regulation of HIV-1 Reverse Transcriptase by ATP for Nucleotide Selection
BACKGROUND: Human immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) is a DNA polymerase that converts viral RNA genomes into proviral DNAs. How HIV-1 RT regulates nucleotide selectivity is a central issue for genetics and the nucleoside analog RT inhibitor (NRTI) resistance of HIV-1. ME...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2810339/ https://ncbi.nlm.nih.gov/pubmed/20111609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008867 |
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