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Time-dependent insulin oligomer reaction pathway prior to fibril formation: Cooling and seeding
The difficulty in identifying the toxic agents in all amyloid-related diseases is likely due to the complicated kinetics and thermodynamics of the nucleation process and subsequent fibril formation. The slow progression of these diseases suggests that the formation, incorporation and/or action of to...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2737737/ https://ncbi.nlm.nih.gov/pubmed/19408310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22417 |
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