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Evaluating Nuclei Concentration in Amyloid Fibrillation Reactions Using Back-Calculation Approach

BACKGROUND: In spite of our extensive knowledge of the more than 20 proteins associated with different amyloid diseases, we do not know how amyloid toxicity occurs or how to block its action. Recent contradictory reports suggest that the fibrils and/or the oligomer precursors cause toxicity. An esti...

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Bibliografiske detaljer
Main Authors: Sorci, Mirco, Silkworth, Whitney, Gehan, Timothy, Belfort, Georges
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098880/
https://ncbi.nlm.nih.gov/pubmed/21625464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020072
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