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Evaluating Nuclei Concentration in Amyloid Fibrillation Reactions Using Back-Calculation Approach

BACKGROUND: In spite of our extensive knowledge of the more than 20 proteins associated with different amyloid diseases, we do not know how amyloid toxicity occurs or how to block its action. Recent contradictory reports suggest that the fibrils and/or the oligomer precursors cause toxicity. An esti...

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Detalles Bibliográficos
Main Authors: Sorci, Mirco, Silkworth, Whitney, Gehan, Timothy, Belfort, Georges
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098880/
https://ncbi.nlm.nih.gov/pubmed/21625464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020072
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