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Mutations and Seeding of Amylin Fibril-Like Oligomers

Seeding a protein solution with pre-formed fibrils can enhance dramatically the growth rate of amyloids. As the seeds do not need to be of the same protein, seeding may account for the observed correlations between amyloid diseases. In an effort to understand better the molecular mechanisms behind c...

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Detalhes bibliográficos
Main Authors: Bernhardt, Nathan A, Berhanu, Workalemahu M., Hansmann, Ulrich H. E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893025/
https://ncbi.nlm.nih.gov/pubmed/24294935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp409777p
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