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Inter-Species Cross-Seeding: Stability and Assembly of Rat - Human Amylin Aggregates

Diseases such as type 2 diabetes, Alzheimer’s and Parkinson’s share as common feature the accumulation of mis-folded disease-specific protein aggregates into fibrillar structures, or plaques. These fibrils may either be toxic by themselves, or act as reservoirs for smaller cytotoxic oligomers. This...

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Detalhes bibliográficos
Main Authors: Berhanu, Workalemahu M., Hansmann, Ulrich H. E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014569/
https://ncbi.nlm.nih.gov/pubmed/24810618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097051
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