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Sex, Age and Regional Differences in L-Type Calcium Current are important determinants of arrhythmia phenotype in Rabbit Hearts with drug induced Long QT type 2
In congenital and acquired long QT type 2 (LQT2), women are more vulnerable than men to Torsade de Pointes (TdP) but in pre-pubertal rabbits (and children), the arrhythmia phenotype is reversed; yet females still have longer action potential durations (APDs) than males. Thus, sex-differences in K(+)...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2737508/ https://ncbi.nlm.nih.gov/pubmed/18436794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.173740 |
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