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Cytosolic Ca(2+) triggers early afterdepolarizations and torsade de pointes in rabbit hearts with type 2 long QT syndrome

The role of intracellular Ca(2+) ([Formula: see text]) in triggering early afterdepolarizations (EADs), the origins of EADs and the mechanisms underlying Torsade de Pointes (TdP) were investigated in a model of long QT syndrome (Type 2). Perfused rabbit hearts were stained with RH327 and Rhod-2/AM t...

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Autori principali: Choi, Bum-Rak, Burton, Francis, Salama, Guy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290501/
https://ncbi.nlm.nih.gov/pubmed/12205194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.024570
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