Sex-differences in sodium/calcium exchange expression is a determinant of the arrhythmia phenotype in pre-pubertal rabbit hearts with Long QT type 2

BACKGROUND: Adult females are more prone to Torsade de Pointes (TdP) than males in long QT type 2 (LQT2) elicited by inhibiting the K(+) current, I(Kr). Sex-differences in the propensity to early afterdepolarizations (EADs) and TdP are reversed in adolescence and correlate with higher levels of L-ty...

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Détails bibliographiques
Auteurs principaux: Chen, Guojun, Yang, Xiaoyan, Kerchner, Laurie J., Salama, Naomi R., Alber, Sean, Shusterman, Vladimir, London, Barry, Salama, Guy
Format: Artigo
Langue:Inglês
Publié: 2010
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163039/
https://ncbi.nlm.nih.gov/pubmed/21193060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2010.12.040
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