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Regional genomic regulation of cardiac sodium–calcium exchanger by oestrogen
Female rabbit hearts are more susceptible to torsade de pointes (TdP) in acquired long QT type 2 than males, in-part due to higher L-type Ca(2+) current (I(Ca,L)) at the base of the heart. In principle, higher Ca(2+) influx via I(Ca,L) should be balanced by higher efflux, perhaps mediated by paralle...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060587/ https://ncbi.nlm.nih.gov/pubmed/21224239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.203398 |
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