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Cardiac Sodium-Calcium Exchanger Is Regulated by Allosteric Calcium and Exchanger Inhibitory Peptide at Distinct Sites

The sarcolemmal Na(+)-Ca(2+) exchanger (NCX) is the main Ca(2+) extrusion mechanism in cardiac myocytes and is thus essential for the regulation of Ca(2+) homeostasis and contractile function. A cytosolic region (f-loop) of the protein mediates regulation of NCX function by intracellular factors inc...

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Detalhes bibliográficos
Main Authors: Maack, Christoph, Ganesan, Anand, Sidor, Agnieszka, O’Rourke, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679901/
https://ncbi.nlm.nih.gov/pubmed/15550690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.RES.0000151334.48676.68
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