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Cardiac Sodium-Calcium Exchanger Is Regulated by Allosteric Calcium and Exchanger Inhibitory Peptide at Distinct Sites
The sarcolemmal Na(+)-Ca(2+) exchanger (NCX) is the main Ca(2+) extrusion mechanism in cardiac myocytes and is thus essential for the regulation of Ca(2+) homeostasis and contractile function. A cytosolic region (f-loop) of the protein mediates regulation of NCX function by intracellular factors inc...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2679901/ https://ncbi.nlm.nih.gov/pubmed/15550690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.RES.0000151334.48676.68 |
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