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Oestrogen upregulates L-type Ca(2+) channels via oestrogen-receptor-α by a regional genomic mechanism in female rabbit hearts

NON-TECHNICAL SUMMARY: Women during their child-bearing years have longer QT intervals in their electrocardiograms than men and are more susceptible to lethal arrhythmias elicited by drugs that delay repolarization. Current theories posit that women have a reduced ‘repolarization reserve’ due to red...

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Main Authors: Yang, Xiaoyan, Chen, Guojun, Papp, Rita, DeFranco, Donald B, Zeng, Fandian, Salama, Guy
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379696/
https://ncbi.nlm.nih.gov/pubmed/22124151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.219501
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