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Fibrinogen-γ C-terminal Fragments Induce Endothelial Barrier Dysfunction and Microvascular Leak via Integrin-mediated and RhoA-dependent Mechanism

OBJECTIVES: The purposes of this study were to characterize the direct effect of the C-terminal fragment of fibrinogen γ chain (γC)on microvascular endothelial permeability and to examine its molecular mechanism of action. METHODS AND RESULTS: Intravital microscopy was performed to measure albumin e...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Guo, Mingzhang, Daines, Dayle, Tang, Jing, Shen, Qiang, Perrin, Rachel M., Takada, Yoshikazu, Yuan, Sarah Y., Wu, Mack H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737386/
https://ncbi.nlm.nih.gov/pubmed/19122172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.108.180950
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