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Fibrinogen-γ C-terminal Fragments Induce Endothelial Barrier Dysfunction and Microvascular Leak via Integrin-mediated and RhoA-dependent Mechanism
OBJECTIVES: The purposes of this study were to characterize the direct effect of the C-terminal fragment of fibrinogen γ chain (γC)on microvascular endothelial permeability and to examine its molecular mechanism of action. METHODS AND RESULTS: Intravital microscopy was performed to measure albumin e...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2737386/ https://ncbi.nlm.nih.gov/pubmed/19122172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.108.180950 |
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