Focal adhesion kinase and Src mediate microvascular hyperpermeability caused by fibrinogen- γC- terminal fragments

OBJECTIVES: We previously reported microvascular leakage resulting from fibrinogen-γ chain C-terminal products (γC) occurred via a RhoA-dependent mechanism. The objective of this study was to further elucidate the signaling mechanism by which γC induces endothelial hyperpermeability. Since it is kno...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Guo, Xiaohua, Eitnier, Rebecca A., Beard, Richard S., Meegan, Jamie E., Yang, Xiaoyuan, Aponte, Alexandra M., Wang, Fang, Nelson, Peter R., Wu, Mack H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192500/
https://ncbi.nlm.nih.gov/pubmed/32352989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0231739
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