Neuronal release of proBDNF

Pro–brain-derived neurotrophic factor (proBDNF) and mature BDNF utilize distinct receptors to mediate divergent neuronal actions. Using new tools to quantitate endogenous BDNF isoforms, we found that mouse neurons secrete both proBDNF and mature BDNF. The highest levels of proBDNF and p75 were obser...

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Detaylı Bibliyografya
Asıl Yazarlar: Yang, Jianmin, Siao, Chia-Jen, Nagappan, Guhan, Marinic, Tina, Jing, Deqiang, McGrath, Kelly, Chen, Zhe-Yu, Mark, Willie, Tessarollo, Lino, Lee, Francis S, Lu, Bai, Hempstead, Barbara L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737352/
https://ncbi.nlm.nih.gov/pubmed/19136973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2244
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