Neuronal release of proBDNF

Pro–brain-derived neurotrophic factor (proBDNF) and mature BDNF utilize distinct receptors to mediate divergent neuronal actions. Using new tools to quantitate endogenous BDNF isoforms, we found that mouse neurons secrete both proBDNF and mature BDNF. The highest levels of proBDNF and p75 were obser...

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Hlavní autoři: Yang, Jianmin, Siao, Chia-Jen, Nagappan, Guhan, Marinic, Tina, Jing, Deqiang, McGrath, Kelly, Chen, Zhe-Yu, Mark, Willie, Tessarollo, Lino, Lee, Francis S, Lu, Bai, Hempstead, Barbara L
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737352/
https://ncbi.nlm.nih.gov/pubmed/19136973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2244
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