ProBDNF negatively regulates neuronal remodeling, synaptic transmission and synaptic plasticity in hippocampus

Experience-dependent plasticity shapes postnatal development of neural circuits, but the mechanisms that refine dendritic arbors, remodel spines, and impair synaptic activity are poorly understood. Mature brain-derived neurotrophic factor (BDNF) modulates neuronal morphology and synaptic plasticity,...

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Main Authors: Yang, Jianmin, Harte-Hargrove, Lauren C., Siao, Chia-Jen, Marinic, Tina, Clarke, Roshelle, Ma, Qian, Jing, Deqiang, LaFrancois, John J., Bath, Kevin G., Mark, Willie, Ballon, Douglas, Lee, Francis S., Scharfman, Helen E., Hempstead, Barbara L.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118923/
https://ncbi.nlm.nih.gov/pubmed/24746813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.03.040
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