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ProBDNF negatively regulates neuronal remodeling, synaptic transmission and synaptic plasticity in hippocampus
Experience-dependent plasticity shapes postnatal development of neural circuits, but the mechanisms that refine dendritic arbors, remodel spines, and impair synaptic activity are poorly understood. Mature brain-derived neurotrophic factor (BDNF) modulates neuronal morphology and synaptic plasticity,...
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| Auteurs principaux: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4118923/ https://ncbi.nlm.nih.gov/pubmed/24746813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.03.040 |
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