Glutamic Acid Decarboxylase-Derived Epitopes with Specific Domains Expand CD4(+)CD25(+) Regulatory T Cells

BACKGROUND: CD4(+)CD25(+) regulatory T cell (Treg)-based immunotherapy is considered a promising regimen for controlling the progression of autoimmune diabetes. In this study, we tested the hypothesis that the therapeutic effects of Tregs in response to the antigenic epitope stimulation depend on th...

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Main Authors: Chen, Guojiang, Han, Gencheng, Feng, Jiannan, Wang, Jianan, Wang, Renxi, Xu, Ruonan, Shen, Beifen, Qian, Jiahua, Li, Yan
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736381/
https://ncbi.nlm.nih.gov/pubmed/19759824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007034
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