Glutamic Acid Decarboxylase-Derived Epitopes with Specific Domains Expand CD4(+)CD25(+) Regulatory T Cells

BACKGROUND: CD4(+)CD25(+) regulatory T cell (Treg)-based immunotherapy is considered a promising regimen for controlling the progression of autoimmune diabetes. In this study, we tested the hypothesis that the therapeutic effects of Tregs in response to the antigenic epitope stimulation depend on th...

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Detalhes bibliográficos
Main Authors: Chen, Guojiang, Han, Gencheng, Feng, Jiannan, Wang, Jianan, Wang, Renxi, Xu, Ruonan, Shen, Beifen, Qian, Jiahua, Li, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736381/
https://ncbi.nlm.nih.gov/pubmed/19759824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007034
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