CD8(+) regulatory T cells are responsible for GAD-IgG gene-transferred tolerance induction in NOD mice

Our previous studies demonstrated that lipopolysaccharide (LPS)-stimulated splenocytes, retrovirally transduced with a glutamate decarboxylate 65 (GAD) and immunoglobulin G (IgG) fusion construct, can protect non-obese diabetic (NOD) mice from diabetes by inducing GAD-specific tolerance, and also th...

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Detalhes bibliográficos
Main Authors: Wang, Renxi, Han, Gencheng, Song, Lun, Wang, Jianan, Chen, Guojiang, Xu, Ruonan, Yu, Ming, Qian, Jiahua, Shen, Beifen, Li, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632702/
https://ncbi.nlm.nih.gov/pubmed/18624731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.02884.x
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