Critical role for thymic CD19(+)CD5(+)CD1d(hi)IL-10(+) regulatory B cells in immune homeostasis

This study tested the hypothesis that besides the spleen, LNs, peripheral blood, and thymus contain a regulatory IL-10-producing CD19(+)CD5(+)CD1d(high) B cell subset that may play a critical role in the maintenance of immune homeostasis. Indeed, this population was identified in the murine thymus,...

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Publicat a:J Leukoc Biol
Autors principals: Xing, Chen, Ma, Ning, Xiao, He, Wang, Xiaoqian, Zheng, Mingke, Han, Gencheng, Chen, Guojiang, Hou, Chunmei, Shen, Beifen, Li, Yan, Wang, Renxi
Format: Artigo
Idioma:Inglês
Publicat: Society for Leukocyte Biology 2015
Matèries:
Inflammation, Extracellular Mediators, & Effector Molecules
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477891/
https://ncbi.nlm.nih.gov/pubmed/25516754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A0414-213RR
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