Disruption of estrogen receptor signaling enhances intestinal neoplasia in Apc(Min/+) mice

Estrogen receptors (ERs) [ERα (Esr1) and ERβ (Esr2)] are expressed in the human colon, but during the multistep process of colorectal carcinogenesis, expression of both ERα and ERβ is lost, suggesting that loss of ER function might promote colorectal carcinogenesis. Through crosses between an ERα kn...

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Detalles Bibliográficos
Autores principales: Cleveland, Alicia G., Oikarinen, Seija I., Bynoté, Kimberly K., Marttinen, Maija, Rafter, Joseph J., Gustafsson, Jan-Åke, Roy, Shyamal K., Pitot, Henry C., Korach, Kenneth S., Lubahn, Dennis B., Mutanen, Marja, Gould, Karen A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2009
Materias:
Carcinogenesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736300/
https://ncbi.nlm.nih.gov/pubmed/19520794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp132
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