Disruption of estrogen receptor signaling enhances intestinal neoplasia in Apc(Min/+) mice

Estrogen receptors (ERs) [ERα (Esr1) and ERβ (Esr2)] are expressed in the human colon, but during the multistep process of colorectal carcinogenesis, expression of both ERα and ERβ is lost, suggesting that loss of ER function might promote colorectal carcinogenesis. Through crosses between an ERα kn...

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Bibliografische gegevens
Hoofdauteurs: Cleveland, Alicia G., Oikarinen, Seija I., Bynoté, Kimberly K., Marttinen, Maija, Rafter, Joseph J., Gustafsson, Jan-Åke, Roy, Shyamal K., Pitot, Henry C., Korach, Kenneth S., Lubahn, Dennis B., Mutanen, Marja, Gould, Karen A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2009
Onderwerpen:
Carcinogenesis
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736300/
https://ncbi.nlm.nih.gov/pubmed/19520794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp132
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