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Disruption of estrogen receptor signaling enhances intestinal neoplasia in Apc(Min/+) mice
Estrogen receptors (ERs) [ERα (Esr1) and ERβ (Esr2)] are expressed in the human colon, but during the multistep process of colorectal carcinogenesis, expression of both ERα and ERβ is lost, suggesting that loss of ER function might promote colorectal carcinogenesis. Through crosses between an ERα kn...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2009
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2736300/ https://ncbi.nlm.nih.gov/pubmed/19520794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp132 |
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