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Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFκB
We describe a highly efficient use of lentiviral validation-based insertional mutagenesis (VBIM) to generate large populations of mammalian cells in which a strong promoter is inserted into many different genomic loci, causing greatly increased expression of downstream sequences. Many different sele...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2736141/ https://ncbi.nlm.nih.gov/pubmed/19805303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908560106 |
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