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HI: haplotype improver using paired-end short reads

Summary: We present a program to improve haplotype reconstruction by incorporating information from paired-end reads, and demonstrate its utility on simulated data. We find that given a fixed coverage, longer reads (implying fewer of them) are preferable. Availability: The executable and user manual...

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Detalhes bibliográficos
Main Authors: Long, Quan, MacArthur, Daniel, Ning, Zemin, Tyler-Smith, Chris
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735667/
https://ncbi.nlm.nih.gov/pubmed/19570807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp412
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