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Complete but curtailed T cell response to very low affinity antigen
Following an infection, CD8(+) T cells are activated and undergo a characteristic kinetic sequence of rapid expansion, subsequent contraction and formation of memory cells1–3. The pool of naïve T cell clones is diverse and contains cells bearing T cell antigen receptors (TCR) that differ in their af...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2735344/ https://ncbi.nlm.nih.gov/pubmed/19182777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07657 |
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