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Complete but curtailed T cell response to very low affinity antigen

Following an infection, CD8(+) T cells are activated and undergo a characteristic kinetic sequence of rapid expansion, subsequent contraction and formation of memory cells1–3. The pool of naïve T cell clones is diverse and contains cells bearing T cell antigen receptors (TCR) that differ in their af...

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Bibliografische gegevens
Hoofdauteurs: Zehn, Dietmar, Lee, Sarah Y., Bevan, Michael J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735344/
https://ncbi.nlm.nih.gov/pubmed/19182777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07657
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