Crystal structure of the complete integrin αVβ3 ectodomain plus an α/β transmembrane fragment

We determined the crystal structure of 1TM-αVβ3, which represents the complete unconstrained ectodomain plus short C-terminal transmembrane stretches of the αV and β3 subunits. 1TM-αVβ3 is more compact and less active in solution when compared with ΔTM-αVβ3, which lacks the short C-terminal stretche...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Xiong, Jian-Ping, Mahalingham, Bhuvaneshwari, Alonso, Jose Luis, Borrelli, Laura Ann, Rui, Xianliang, Anand, Saurabh, Hyman, Bradley T., Rysiok, Thomas, Müller-Pompalla, Dirk, Goodman, Simon L., Arnaout, M. Amin
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Rockefeller University Press 2009
विषय:
Research Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733745/
https://ncbi.nlm.nih.gov/pubmed/19704023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200905085
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