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R1441C mutation in LRRK2 impairs dopaminergic neurotransmission in mice
Dominantly inherited mutations in leucine-rich repeat kinase 2 (LRRK2) are a common genetic cause of Parkinson's disease (PD). The importance of the R1441 residue in the pathogenesis is highlighted by the identification of three distinct missense mutations. To investigate the pathogenic mechani...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2732807/ https://ncbi.nlm.nih.gov/pubmed/19667187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906334106 |
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