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Effects of LRRK2 Inhibitors on Nigrostriatal Dopaminergic Neurotransmission
INTRODUCTION: Mutations in leucine‐rich repeat kinase 2 (LRRK2) are the most prevalent cause of familial and sporadic Parkinson's disease (PD). Because most pathogenic LRRK2 mutations result in enhanced kinase activity, it suggests that LRRK2 inhibitors may serve as a potential treatment for PD...
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| Yayımlandı: | CNS Neurosci Ther |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
John Wiley and Sons Inc.
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5248597/ https://ncbi.nlm.nih.gov/pubmed/27943591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12660 |
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