Effects of LRRK2 Inhibitors on Nigrostriatal Dopaminergic Neurotransmission

INTRODUCTION: Mutations in leucine‐rich repeat kinase 2 (LRRK2) are the most prevalent cause of familial and sporadic Parkinson's disease (PD). Because most pathogenic LRRK2 mutations result in enhanced kinase activity, it suggests that LRRK2 inhibitors may serve as a potential treatment for PD...

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Bibliografische gegevens
Gepubliceerd in:CNS Neurosci Ther
Hoofdauteurs: Qin, Qi, Zhi, Lian‐Teng, Li, Xian‐Ting, Yue, Zhen‐Yu, Li, Guo‐Zhong, Zhang, Hui
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2016
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Original Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248597/
https://ncbi.nlm.nih.gov/pubmed/27943591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12660
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