Llwytho...

α-Synuclein and LRRK2: Partners in Crime

In this issue of Neuron, Lin et al. report that LRRK2 modulates age-related neurodegeneration caused by overexpression of α-synuclein in the forebrain of transgenic mice. Overexpression of LRRK2 accelerates the progression of α-synuclein-mediated neuropathological changes, whereas deletion of LRRK2...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tong, Youren, Shen, Jie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826885/
https://ncbi.nlm.nih.gov/pubmed/20064381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2009.12.017
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