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α-synuclein, LRRK2 and their interplay in Parkinson’s disease

Of the various genetic factors contributing to the pathogenesis of Parkinson’s disease (PD), only mutations in α-synuclein (α-syn) and LRRK2 genes cause clinical and neuropathological phenotypes closely resembling the sporadic cases. Therefore, studying the pathophysiological functions of these two...

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Autors principals: Liu, Guoxiang, Aliaga, Leonardo, Cai, Huaibin
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343692/
https://ncbi.nlm.nih.gov/pubmed/22563296
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