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α-synuclein, LRRK2 and their interplay in Parkinson’s disease

Of the various genetic factors contributing to the pathogenesis of Parkinson’s disease (PD), only mutations in α-synuclein (α-syn) and LRRK2 genes cause clinical and neuropathological phenotypes closely resembling the sporadic cases. Therefore, studying the pathophysiological functions of these two...

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Bibliografische gegevens
Hoofdauteurs: Liu, Guoxiang, Aliaga, Leonardo, Cai, Huaibin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343692/
https://ncbi.nlm.nih.gov/pubmed/22563296
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