The Pharmacokinetics and Pharmacodynamics of Micafungin in Experimental Hematogenous Candida Meningoencephalitis: Implications for Echinocandin Therapy in Neonates

BACKGROUND: Hematogenous Candida meningoencephalitis (HCME) is a relatively frequent manifestation of disseminated candidiasis in neonates that is associated with significant mortality and neurodevelopmental abnormalities. The outcome following antifungal therapy is often suboptimal with few therape...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hope, William W., Mickiene, Diana, Petraitis, Vidmantas, Petraitiene, Ruta, Kelaher, Amy M., Hughes, Joanna E., Cotton, Margaret P., Bacher, John, Keirns, James J., Buell, Donald, Heresi, Gloria, Benjamin, Daniel K., Groll, Andreas H., Drusano, George L., Walsh, Thomas J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732769/
https://ncbi.nlm.nih.gov/pubmed/18171300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/524063
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