Efficacy and Pharmacokinetics of Fosmanogepix (APX001) in the Treatment of Candida Endophthalmitis and Hematogenous Meningoencephalitis in Nonneutropenic Rabbits

Candida endophthalmitis is a serious sight-threatening complication of candidemia that may occur before or during antifungal therapy. Hematogenous Candida meningoencephalitis (HCME) is also a serious manifestation of disseminated candidiasis in premature infants, immunosuppressed children, and immun...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Petraitiene, Ruta, Petraitis, Vidmantas, Maung, Bo Bo Win, Mansbach, Robert S., Hodges, Michael R., Finkelman, Malcolm A., Shaw, Karen Joy, Walsh, Thomas J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2021
Schlagworte:
Experimental Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092521/
https://ncbi.nlm.nih.gov/pubmed/33361304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01795-20
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