Pharmacodynamics of Posaconazole in Experimental Invasive Pulmonary Aspergillosis: Utility of Serum Galactomannan as a Dynamic Endpoint of Antifungal Efficacy

Aspergillus galactomannan antigenemia is an accepted tool for the diagnosis of invasive pulmonary aspergillosis (IPA) in neutropenic patients. Little is known, however, about the utility of this biomarker to assess the efficacy of antifungal therapies. The pharmacokinetics (PK) and pharmacodynamics...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Gastine, Silke, Hope, William, Hempel, Georg, Petraitiene, Ruta, Petraitis, Vidmantas, Mickiene, Diana, Bacher, John, Walsh, Thomas J., Groll, Andreas H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7848991/
https://ncbi.nlm.nih.gov/pubmed/33168606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01574-20
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