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How ATR turns on: TopBP1 goes on ATRIP with ATR
In this issue of Genes & Development, Mordes and colleagues (pp. 1478–1489) reveal intriguing mechanistic insights into activation of the ATR (ATM and Rad3-related) kinase critical for DNA damage resistance. They identify conserved regulatory domains within ATR and its binding partner ATRIP (ATR...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Cold Spring Harbor Laboratory Press
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2732414/ https://ncbi.nlm.nih.gov/pubmed/18519633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1685108 |
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