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Dopamine-Induced Conformational Changes in Alpha-Synuclein
BACKGROUND: Oligomerization and aggregation of α-synuclein molecules play a major role in neuronal dysfunction and loss in Parkinson's disease [1]. However, α-synuclein oligomerization and aggregation have mostly been detected indirectly in cells using detergent extraction methods [2], [3], [4]...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2731858/ https://ncbi.nlm.nih.gov/pubmed/19730729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006906 |
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