TGF-β1 modulates focal adhesion kinase expression in rat intestinal epithelial IEC-6 cells via stimulatory and inhibitory Smad binding elements

TGF-β and FAK modulate cell migration, differentiation, proliferation and apoptosis, and TGF-β promotes FAK transcription in intestinal epithelial cells via Smad-dependent and independent pathways. We utilized a 1320bp FAK promoter-luciferase construct to characterize basal and TGF-β-mediated FAK ge...

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Autors principals: Walsh, Mary F., Ampasala, Dinakar R., Rishi, Arun K., Basson, Marc D.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730956/
https://ncbi.nlm.nih.gov/pubmed/19059368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2008.11.002
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