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TGF-β1 modulates focal adhesion kinase expression in rat intestinal epithelial IEC-6 cells via stimulatory and inhibitory Smad binding elements
TGF-β and FAK modulate cell migration, differentiation, proliferation and apoptosis, and TGF-β promotes FAK transcription in intestinal epithelial cells via Smad-dependent and independent pathways. We utilized a 1320bp FAK promoter-luciferase construct to characterize basal and TGF-β-mediated FAK ge...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2730956/ https://ncbi.nlm.nih.gov/pubmed/19059368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2008.11.002 |
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